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Spontaneous apoptosis in chronic lymphocytic leukemia and its relationship to clinical and cell kinetic parameters

✍ Scribed by Gislaine B. Oliveira; Fernanda G. Pereira; Konradin Metze; Irene Lorand-Metze


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
116 KB
Volume
46
Category
Article
ISSN
0196-4763

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## Abstract In order to identify regulatory genes involved in the development of an apoptosis‐resistant phenotype in patients with chemotherapy refractory B‐cell chronic lymphocytic leukemia (B‐CLL) expression of apoptosis‐regulating genes in B‐CLL cells was quantified using cDNA arrays and RT‐PCR.