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Spontaneous and Radiation-Induced Benign Tumors in Parabiont Rats

✍ Scribed by S. Warren, O. Gates, C. E. Brown, R. N. Chute and M. W. Porter


Book ID
124615775
Publisher
Bioone
Year
1978
Tongue
English
Weight
306 KB
Volume
75
Category
Article
ISSN
0033-7587

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A high frequency of point mutations at codon 12 of the Ki-ras gene has previously been reported for rat kidney mesenchymal tumors induced by methylating N-nitroso compounds. In this study, we analyzed renal tumors with divergent histogenesis, i.e., mesenchymal tumors (sarcomas), cortical epithelial