Splitless injection-development and state of the art. Including a comparison of matrix (“dirt”) effects in conventional and PTV splitless injection

✍ Scribed by Grob, K. ;Läubli, Th. ;Brechbühler, B.

• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 771 KB
• Volume: 11
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240110607

✦ Synopsis

Kurt Grob introduced splitless injection in 1969. He elaborated most of the working guidelines including the techniques required for reconcentrating the broad initial bands, i.e. the solvent effects and cold trapping. He also designed avaporizing injector suited for splitless injection. Nevertheless, splitless injection is still often carried out using inappropriate conditions, and many of today's vaporizing injectors are not suited for splitless injection. No autosampler is available that introduces the sample at the appropriate position. Conventional splitless injection is compared to PTV splitless injection for the range of samples that cannot be handled by the anyway superior oncolumn injection, i.e. sample with high loads of involatile byproducts. There is a clear preference for PTV splitless injection as matrix effects observed in conventional splitless injection were found to be substantially reduced or even eliminated.