## Abstract Duchenne's muscular dystrophy (DMD), which affects 1/3500 live male births, involves a progressive degeneration of skeletal and cardiac muscle, leading to early death. The protein dystrophin is lacking in DMD and present, but defective, in the allelic, less severe, Becker muscular dystr
β¦ LIBER β¦
Split genes and muscular dystrophy
β Scribed by Dr. Robinson Lewis
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 668 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
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Golden retriever muscular dystrophy (GRMD), the canine model of Duchenne muscular dystrophy (DMD), is caused by a splice site mutation in the dystrophin gene. This mutation predicts a premature termination codon in exon 8 and a peptide that is 5% the size of normal dystrophin. Western blot analysis