Phase II clinical trial with 5-fluoroura
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Scott Wadler; Hilda Haynes; Jonathan J. Beitler; Xiaoping Hu; Stanley Fell; Marg
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Article
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1996
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John Wiley and Sons
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English
โ 393 KB
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## Background: Recombinant interferon-alpha (ifn) augments the cytotoxicity of both 5-fluorouracil (5-fu) and cisplatin in vitro. a phase ii study of 5-fu and ifn resulted in response rates of 25-27% in patients with metastatic esophageal carcinoma. ## Methods: A phase ii trial was initiated to d