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Splice variants of TLE family genes and up-regulation of a TLE3 isoform in prostate tumors

✍ Scribed by Helder I. Nakaya; Felipe C. Beckedorff; Maria L. Baldini; Angela A. Fachel; Eduardo M. Reis; Sergio Verjovski-Almeida


Book ID
116295856
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
369 KB
Volume
364
Category
Article
ISSN
0006-291X

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In a small-cell lung carcinoma (SCLC) tumor specimen as well as in 3 cell lines derived from SCLC biopsies obtained from the same patient at successive times during the clinical course, either the N-myc gene or the c-myc gene appeared to be amplified and expressed. The initial tumor specimen, a lymp