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Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: Expression and hypoxic regulation

✍ Scribed by Oleksandr H. Minchenko; Tsutomu Ogura; Iryna L. Opentanova; Dmytro O. Minchenko; Hiroyasu Esumi

Book ID: 106457670
Publisher: Springer
Year: 2005
Tongue: English
Weight: 476 KB
Volume: 280
Category: Article
ISSN: 0300-8177
DOI: 10.1007/s11010-005-8009-6

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## Abstract Recently, it has been demonstrated that fructose‐2,6‐bisphosphate (F2,6BP) protects skeletal muscle 6‐phosphofructo‐1‐kinase (PFK) from thermal inactivation (50 °C) and against the deleterious effects of guanidinium hydrochloride (GdmCl). On the other hand, ATP, when added at its inhibi