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Splenic focal lesions as manifestation of sarcoidosis: Characterization with contrast-enhanced sonography

✍ Scribed by María José Pérez-Grueso; Alejandro Repiso; Rafael Gómez; Concepción Gonzalez; Tomás de Artaza; Julio Valle; Almudena García; Jose María Carrobles

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 163 KB
Volume: 35
Category: Article
ISSN: 0091-2751
DOI: 10.1002/jcu.20322

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✦ Synopsis

Abstract

We report the case of a 74‐year‐old woman with elevated liver enzyme levels in whom abdominal sonographic examination revealed a diffusely heterogeneous liver parenchyma and multiple hypoechoic subcentimetric splenic nodules. Contrast‐enhanced sonography (CEUS) revealed that the splenic focal lesions did not enhance. CT examination revealed a low‐density, multinodular pattern both in the liver and in the spleen. Core biopsy of 1 hepatic nodule revealed noncaseating epithelioid cell granuloma, and the patient was diagnosed with systemic sarcoidosis. CEUS has shown to be useful in the diagnosis of focal hepatic lesions, but studies referring to splenic lesions are lacking. © 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2007

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## Abstract ## Purpose. To compare contrast‐enhanced sonography (CEUS) with contrast‐enhanced CT in the assessment of nontraumatic focal lesions of the spleen. ## Methods. CEUS and CT findings in 22 patients with fever of unknown origin and ultrasound‐detected splenic focal lesions were analyzed