Some patients with thrombotic thrombocytopenic purpura (TTP) remain plasmaexchange-dependent for prolonged periods of time. This exposes patients to risk, uses substantial resources, and requires prolonged hospitalization. We have splenectomized 7 such patients following 25-42 plasma exchanges while
Splenectomy in thrombotic thrombocytopenic purpura
✍ Scribed by Furlan, Miha; Lämmle, Bernhard
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 48 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0361-8609
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## Abstract The mainstay of treatment for thrombotic thrombocytopenic purpura (TTP) is plasma exchange (PE), but the role of splenectomy is still undefined. The records of all patients with TTP at a single center over a 20‐year period were retrospectively reviewed. Response to plasma exchange was d
Coagulo-fibrinolytic factors were studied in five patients suffering from thrombotic thrombocytopenic purpura (TTP). The change in coagulation factors in the acute stage was mild compared with that found in disseminated intravascular coagulation (DIC). We observed a slight increase of fibrin-fibrino