Spirostanol Saponins from the Fibrous Roots of Ophiopogon japonicus (Thunb.) Ker-Gawl
✍ Scribed by Chang-Ling Duan; Yu-Juan Li; Peng Li; Yong Jiang; Jian-Xun Liu; Peng-Fei Tu
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- German
- Weight
- 176 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Three new steroidal saponins, (25__R__)‐ruscogenin‐3‐yl α‐L‐rhamnopyranosyl‐(1→2)‐[β‐D‐xylopyranosyl‐(1→4)]‐β‐D‐glucopyranoside (1), diosgenin‐3‐yl 2‐O‐acetyl‐α‐L‐rhamnopyranosyl‐(1→2)‐[β‐D‐xylopyranosyl‐(1→4)]‐β‐D‐glucopyranoside (2), and pennogenin‐3‐yl 2‐O‐acetyl‐α‐L‐rhamnopyranosyl‐(1→2)‐[β‐D‐xylopyranosyl‐(1→4)]‐β‐D‐glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus (Thunb.) Ker‐Gawl. Their structures were determined by spectroscopic methods including IR, HR‐ESI‐MS, and 1D‐ and 2D‐NMR. All of these three steroidal saponins exhibited weak cytotoxicities against Hela and Hep2 cell lines.