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Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats

✍ Scribed by FUJISAWA, GENRO; OKADA, KOJI; MUTO, SHIGEAKI; FUJITA, NOBUYA; ITABASHI, NAOKI; KUSANO, EIJI; ISHIBASHI, SHUN

Book ID
109066632
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
272 KB
Volume
66
Category
Article
ISSN
0085-2538

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This study investigated the protective effect of the angiotensin converting enzyme inhibitor, ramipril, on endothelium-dependent responses in arteries from control (CON) and streptozotocin-induced (STZ) diabetic rats. Three hypotheses were tested: 1) there is an endothelium-dependent component to th