✦ LIBER ✦

Spirodiketopiperazine-based CCR5 antagonist: Discovery of an antiretroviral drug candidate

✍ Scribed by Rena Nishizawa; Toshihiko Nishiyama; Katsuya Hisaichi; Chiaki Minamoto; Naoki Matsunaga; Yoshikazu Takaoka; Hisao Nakai; Stephen Jenkinson; Wieslaw M. Kazmierski; Hideaki Tada; Kenji Sagawa; Shiro Shibayama; Daikichi Fukushima; Kenji Maeda; Hiroaki Mitsuya

Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 433 KB
Volume: 21
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2010.12.109

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Spirodiketopiperazi

ChemInform Abstract: Spirodiketopiperazine-Based CCR5 Antagonist: Discovery of an Antiretroviral Drug Candidate.

✍ Rena Nishizawa; et al. et al. 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

## Abstract Isomeric spirodiketopiperazines are separately synthesized as potential orally‐available anti‐HIV drug candidates.

ChemInform Abstract: Discovery of ((1S,3

ChemInform Abstract: Discovery of ((1S,3R)-1-Isopropyl-2-( (3S,4S)-3-methoxy-tetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(5- (trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methanone (I), PF-4254196, a CCR2 Antagonist with an Improved Cardiovascular Profile.

✍ Robert O. Hughes; et al. et al. 📂 Article 📅 2012 🏛 John Wiley and Sons ⚖ 12 KB 👁 1 views