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Spirocyclohexadienones. Part 5. Synthesis of 2-R-7a-Methyl-3-(spirocyclohexa-2,5-dien-4-one)perhydro-1-indolines.

✍ Scribed by V. A. Glushkov; O. G. Ausheva; Yu. V. Shklyaev


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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## Abstract Two benzodiazepines, Diazepam and Flunitrazepam, labeled with carbon‐14 in position 5 of the diazepine ring have been synthesized. Use of a condensation between iminochlorides and ^14^C‐benzonitriles, followed by exhaustive methylation of the resulting quinazolines and hydrolyses is des