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Spirocycle assembly through selective tandem ring closing metathesis reactions

✍ Scribed by Martin J. Bassindale; Peter Hamley; Andreas Leitner; Joseph P.A. Harrity

Book ID
104261169
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
198 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

A range of functionalised spirocyclic systems have been prepared under mild and neutral conditions by tandem selective ring closing olefin metathesis reactions. Additionally, a marked preference for 5-membered ring closure over 7-membered ring closure was observed which appears to be a result of a kinetically favoured cyclisation process.

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