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Spine microdomains for postsynaptic signaling and plasticity

โœ Scribed by Thomas M. Newpher; Michael D. Ehlers


Book ID
113926309
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
486 KB
Volume
19
Category
Article
ISSN
0962-8924

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The dendritic spine may be considered a fusion of a specialized actin-based structure akin to filopodia and lamellopodia, with an excitatory postsynaptic density containing glutamate receptors and signal-transducing machinery. This specialized neuronal microdomain is the site of the majority of exci