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Spine loss and other dendritic abnormalities in epilepsy

✍ Scribed by John W. Swann; Salwa Al-Noori; Minghui Jiang; Chong L. Lee

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
372 KB
Volume
10
Category
Article
ISSN
1050-9631

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Carboxypeptidase E knockout mice exhibit
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## Abstract Carboxypeptidase E (CPE) is involved in maturation of neuropeptides and sorting of brain‐derived neurotrophic factor (BDNF) to the regulated pathway for activity‐dependent secretion from CNS neurons. CPE knockout (CPE‐KO) mice have many neurological deficits, including deficits in learn