## Abstract The generation of cellular diversity in the developing embryonic central nervous system of __Drosophila melanogaster__ requires the precise orchestration of several convergent molecular and cellular mechanisms. Most reviews have focused on the formation and specification of neuroblasts
Spindle assembly in Drosophila neuroblasts and ganglion mother cells
β Scribed by Bonaccorsi, Silvia; Giansanti, Maria Grazia; Gatti, Maurizio
- Book ID
- 109827314
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 561 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1465-7392
- DOI
- 10.1038/71378
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Chinese hamster ovary (CHO) cells, which are arrested at the G1/S-phase of the cell cycle with hydroxyurea, enter mitosis prematurely when treated with caffeine [Schlegel and Pardee, 1986; Science 233-1264-1266]. Such mitotic cells with unreplicated genomes (MUGs) can assemble a mitotic spindle and
## Abstract Alterations in chromosomal number and structure are found in most solid malignancies including head and neck squamous cell carcinoma (HNSC), however, the presence of ongoing, chromosomal instability in HNSC and its relation to spindle assembly checkpoint defects has not been formally de