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Spinal muscular atrophy: going beyond the motor neuron

✍ Scribed by Hamilton, Gillian; Gillingwater, Thomas H.

Book ID
122508273
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
450 KB
Volume
19
Category
Article
ISSN
1471-4914

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## Abstract The hereditary neurodegenerative disease spinal muscular atrophy (SMA) with childhood onset is one of the most common genetic causes of infant mortality. The disease is characterized by selective loss of spinal cord motor neurons leading to muscle atrophy and is the result of mutations