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Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia

โœ Scribed by Rui-Xin Zhang; Bing Liu; Linbo Wang; Ke Ren; Jian-Tian Qiao; Brian M. Berman; Lixing Lao

Book ID
116817711
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
823 KB
Volume
118
Category
Article
ISSN
0304-3959

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## Abstract The activation of microglia and astrocytes in the spinal cord is involved in the progress of cancer pain. Propentofylline (PPF), a glial modulating agent, alleviates pain hypersensitivity in neuropathic pain models. The present study investigated the potential roles of PPF in a preclini