Spinal cord injuries typically strike young, previously healthy persons, and leaves the individual with a severe, life-lasting impairment affecting all organ systems. Without adequate management, the risk of severe morbidity and mortality is very high. In contrast state-of-the-art management makes i
Spinal Cord Injury
β Scribed by Joost Verhaagen and John W. McDonald (Eds.)
- Publisher
- Elsevier
- Year
- 2012
- Leaves
- 642
- Series
- Handbook of Clinical Neurology 109
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury.
Comprehensive coverage of the latest scientific understanding of spinal cord injuries
Detailed coverage of current treatment best practices and potential future treatments
*Connects leading edge research programs to future treatment opportunities
β¦ Table of Contents
Content:
Series Page
Page ii
Copyright
Page iv
Handbook of Clinical Neurology 3rd Series
Page v
Foreword
Page vii
Michael J. Aminoff, FranΓ§ois Boller, Dick F. Swaab
Preface
Page ix
Joost Verhaagen, John W. McDonald
List of contributors
Pages xi-xv
Chapter 1 - Development and maturation of the spinal cord: implications of molecular and genetic defects
Pages 3-30
Gregory W.J. Hawryluk, Crystal A. Ruff, Michael G. Fehlings
Chapter 2 - Anatomy and biomechanics of the spinal column and cord
Pages 31-43
Vincent J. Miele, Manohar M. Panjabi, Edward C. Benzel
Chapter 3 - Clinical diagnosis and prognosis following spinal cord injury
Pages 47-62
Anthony S. Burns, Ralph J. Marino, Adam E. Flanders, Heather Flett
Chapter 4 - Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury
Pages 63-75
A. Curt, P.H. Ellaway
Chapter 5 - Concepts of aging with paralysis: Implications for recovery and treatment
Pages 77-84
M. Wirz, V. Dietz
Chapter 6 - Advanced MRI strategies for assessing spinal cord injury
Pages 85-101
Seth A. Smith, James J. Pekar, Peter C.M. Van Zijl
Chapter 7 - Advances in the management of spinal cord and spinal column injuries
Pages 105-130
Alexander Taghva, Daniel J. Hoh, Carl L. Lauryssen
Chapter 8 - Spinal cord injuries in children and adolescents
Pages 131-148
Lawrence C. Vogel, Randall R. Betz, M.J. Mulcahey
Chapter 9 - The changing landscape of spinal cord injury
Pages 149-166
Neringa Juknis, Justin M. Cooper, Oksana Volshteyn
Chapter 10 - Surgical treatments to restore function control in spinal cord injury
Pages 167-179
Michael W. Keith, Allan Peljovich
Chapter 11 - Advances in the rehabilitation management of acute spinal cord injury
Pages 181-195
John F. Ditunno, Diana D. Cardenas, Christopher Formal, Kevin Dalal
Chapter 12 - Spasticity
Pages 197-211
Volker Dietz, Thomas Sinkjaer
Chapter 13 - Disordered cardiovascular control after spinal cord injury
Pages 213-233
Lynne C. Weaver, Jennifer C. Fleming, Christopher J. Mathias, Andrei V. Krassioukov
Chapter 14 - New concepts in the prevention of pressure sores
Pages 235-246
Kath Bogie, Heather L. Powell, Chester H. Ho
Chapter 15 - Functional electrical stimulation for bladder, bowel, and sexual function
Pages 247-257
Graham H. Creasey, Michael D. Craggs
Chapter 16 - Evidence-based therapy for recovery of function after spinal cord injury
Pages 259-274
Susan Harkema, Andrea Behrman, Hugues Barbeau
Chapter 17 - Functional electrical stimulation: restoration of respiratory function
Pages 275-282
Raymond P. Onders
Chapter 18 - Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord injury
Pages 283-296
Charles H. Tator, Karen Minassian, Vivian K. Mushahwar
Chapter 19 - Promoting optimal functioning in spinal cord injury: the role of rehabilitation psychology
Pages 297-314
Stephen T. Wegener, Laura L. Adams, Daniel Rohe
Chapter 20 - The changing field of rehabilitation: optimizing spontaneous regeneration and functional recovery
Pages 317-336
John W. McDonald III, Cristina L. Sadowsky, Argyrios Stampas
Chapter 21 - The longitudinal spinal cord injury: Lessons from intraspinal plexus, cauda equina and medullary conus lesions
Pages 337-354
Thomas Carlstedt, Leif Havton
Chapter 22 - Post-traumatic syringomyelia: CSF hydrodynamic changes following SCI are the driving force in the development of PTSM
Pages 355-367
Christopher B. Shields, Yi Ping Zhang, Lisa B.E. Shields
Chapter 23 - Post-traumatic deformity: prevention and management
Pages 369-384
Joyce Wilson, Jacob M. Buchowski, Keith H. Bridwell, Lawrence G. Lenke
Chapter 24 - Spinal cord injury clinical trials translational process, review of past and proposed acute trials with reference to recommended trial guidelines
Pages 386-397
John Steeves, Andrew Blight
Chapter 25 - Translating preclinical approaches into human application
Pages 399-409
Volker Dietz, Armin Curt
Chapter 26 - Translational spinal cord injury research: preclinical guidelines and challenges
Pages 411-433
Paul J. Reier, Michael A. Lane, Edward D. Hall, Y.D. Teng, Dena R. Howland
Chapter 27 - Brainβmachine interfaces and transcranial stimulation: future implications for directing functional movement and improving function after spinal injury in humans
Pages 435-444
Jose M. Carmena, Leonardo G. Cohen
Chapter 28 - Approaches to repairing the damaged spinal cord: overview
Pages 445-461
Daniel Becker, John W. Mcdonald III
Chapter 29 - Limiting spinal cord injury by pharmacological intervention
Pages 463-484
John V. Priestley, Adina T. Michael-Titus, Wolfram Tetzlaff
Chapter 30 - Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications
Pages 485-502
Samuel David, Rubèn López-Vales, V. Wee Yong
Chapter 31 - Defeating inhibition of regeneration by scar and myelin components
Pages 503-522
James W. Fawcett, Martin E. Schwab, Laura Montani, Nicole Brazda, Hans Werner MΓller
Chapter 32 - Realizing the maximum potential of Schwann cells to promote recovery from spinal cord injury
Pages 523-540
Mary Bartlett Bunge, Patrick Mcghee Wood
Chapter 33 - Repair of central nervous system lesions by transplantation of olfactory ensheathing cells
Pages 541-549
Geoffrey Raisman, S.C. Barnett, Almudena RamΓ³n-Cueto
Chapter 34 - Cell transplantation: stem cells and precursor cells
Pages 551-561
Qilin Cao, Scott R. Whittemore
Chapter 35 - Gene therapy, neurotrophic factors and spinal cord regeneration
Pages 563-574
Armin Blesch, Itzhak Fischer, Mark H. Tuszynski
Chapter 36 - Scaffolds to promote spinal cord regeneration
Pages 575-594
S. Sakiyama-Elbert, P.J. Johnson, S.I. Hodgetts, G.W. Plant, A.R. Harvey
Chapter 37 - Molecular target discovery for neural repair in the functional genomics era
Pages 595-616
Joost Verhaagen, Ronald E. Van kesteren, Koen A.M. Bossers, Harold D. Macgillavry, Matthew R. Mason, August B. Smit
Chapter 38 - Combination therapies
Pages 617-636
M. Oudega, E.J. Bradbury, M.S. Ramer
Index
Pages 637-656
π SIMILAR VOLUMES
<p>We shall not, and those who come after us must not, accept the goals that were not reached yesterday as unsurmountable today or tomorrow. We will strive to render the world of the paralyzed-on-wheels but a transitory stop, and settle for nothing short of optimal recovery. N. Eric Naftchi In man,
<p><span>The spinal cord is comprised of four types of neurons: motor neurons, pre-ganglionic neurons, ascending projection neurons, and spinal interneurons. Interneurons are neurons that process information within local circuits, and have an incredible ability for neuroplasticity, whether due to pe
This is the definitive guide to dealing with the major challenges faced by those with spinal cord injuries, as related to health, finances, and their social support system. It is primarily designed to identify medical and non-medical problems that individuals may face as they live with SCI for a num
<p>In Neurobiology of Spinal Cord Injury, a panel of distinguished researchers review the latest scientific understanding of spinal cord injury (SCI), focusing on the mechanisms causing paralysis after spinal cord trauma, the molecular determinants of neural regeneration, and methods for improving f