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Spinal Cord Injury

✍ Scribed by Joost Verhaagen and John W. McDonald (Eds.)


Publisher
Elsevier
Year
2012
Leaves
642
Series
Handbook of Clinical Neurology 109
Edition
1
Category
Library

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✦ Synopsis


Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury.

Comprehensive coverage of the latest scientific understanding of spinal cord injuries
Detailed coverage of current treatment best practices and potential future treatments
*Connects leading edge research programs to future treatment opportunities

✦ Table of Contents


Content:
Series Page
Page ii

Copyright
Page iv

Handbook of Clinical Neurology 3rd Series
Page v

Foreword
Page vii
Michael J. Aminoff, FranΓ§ois Boller, Dick F. Swaab

Preface
Page ix
Joost Verhaagen, John W. McDonald

List of contributors
Pages xi-xv

Chapter 1 - Development and maturation of the spinal cord: implications of molecular and genetic defects
Pages 3-30
Gregory W.J. Hawryluk, Crystal A. Ruff, Michael G. Fehlings

Chapter 2 - Anatomy and biomechanics of the spinal column and cord
Pages 31-43
Vincent J. Miele, Manohar M. Panjabi, Edward C. Benzel

Chapter 3 - Clinical diagnosis and prognosis following spinal cord injury
Pages 47-62
Anthony S. Burns, Ralph J. Marino, Adam E. Flanders, Heather Flett

Chapter 4 - Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury
Pages 63-75
A. Curt, P.H. Ellaway

Chapter 5 - Concepts of aging with paralysis: Implications for recovery and treatment
Pages 77-84
M. Wirz, V. Dietz

Chapter 6 - Advanced MRI strategies for assessing spinal cord injury
Pages 85-101
Seth A. Smith, James J. Pekar, Peter C.M. Van Zijl

Chapter 7 - Advances in the management of spinal cord and spinal column injuries
Pages 105-130
Alexander Taghva, Daniel J. Hoh, Carl L. Lauryssen

Chapter 8 - Spinal cord injuries in children and adolescents
Pages 131-148
Lawrence C. Vogel, Randall R. Betz, M.J. Mulcahey

Chapter 9 - The changing landscape of spinal cord injury
Pages 149-166
Neringa Juknis, Justin M. Cooper, Oksana Volshteyn

Chapter 10 - Surgical treatments to restore function control in spinal cord injury
Pages 167-179
Michael W. Keith, Allan Peljovich

Chapter 11 - Advances in the rehabilitation management of acute spinal cord injury
Pages 181-195
John F. Ditunno, Diana D. Cardenas, Christopher Formal, Kevin Dalal

Chapter 12 - Spasticity
Pages 197-211
Volker Dietz, Thomas Sinkjaer

Chapter 13 - Disordered cardiovascular control after spinal cord injury
Pages 213-233
Lynne C. Weaver, Jennifer C. Fleming, Christopher J. Mathias, Andrei V. Krassioukov

Chapter 14 - New concepts in the prevention of pressure sores
Pages 235-246
Kath Bogie, Heather L. Powell, Chester H. Ho

Chapter 15 - Functional electrical stimulation for bladder, bowel, and sexual function
Pages 247-257
Graham H. Creasey, Michael D. Craggs

Chapter 16 - Evidence-based therapy for recovery of function after spinal cord injury
Pages 259-274
Susan Harkema, Andrea Behrman, Hugues Barbeau

Chapter 17 - Functional electrical stimulation: restoration of respiratory function
Pages 275-282
Raymond P. Onders

Chapter 18 - Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord injury
Pages 283-296
Charles H. Tator, Karen Minassian, Vivian K. Mushahwar

Chapter 19 - Promoting optimal functioning in spinal cord injury: the role of rehabilitation psychology
Pages 297-314
Stephen T. Wegener, Laura L. Adams, Daniel Rohe

Chapter 20 - The changing field of rehabilitation: optimizing spontaneous regeneration and functional recovery
Pages 317-336
John W. McDonald III, Cristina L. Sadowsky, Argyrios Stampas

Chapter 21 - The longitudinal spinal cord injury: Lessons from intraspinal plexus, cauda equina and medullary conus lesions
Pages 337-354
Thomas Carlstedt, Leif Havton

Chapter 22 - Post-traumatic syringomyelia: CSF hydrodynamic changes following SCI are the driving force in the development of PTSM
Pages 355-367
Christopher B. Shields, Yi Ping Zhang, Lisa B.E. Shields

Chapter 23 - Post-traumatic deformity: prevention and management
Pages 369-384
Joyce Wilson, Jacob M. Buchowski, Keith H. Bridwell, Lawrence G. Lenke

Chapter 24 - Spinal cord injury clinical trials translational process, review of past and proposed acute trials with reference to recommended trial guidelines
Pages 386-397
John Steeves, Andrew Blight

Chapter 25 - Translating preclinical approaches into human application
Pages 399-409
Volker Dietz, Armin Curt

Chapter 26 - Translational spinal cord injury research: preclinical guidelines and challenges
Pages 411-433
Paul J. Reier, Michael A. Lane, Edward D. Hall, Y.D. Teng, Dena R. Howland

Chapter 27 - Brain–machine interfaces and transcranial stimulation: future implications for directing functional movement and improving function after spinal injury in humans
Pages 435-444
Jose M. Carmena, Leonardo G. Cohen

Chapter 28 - Approaches to repairing the damaged spinal cord: overview
Pages 445-461
Daniel Becker, John W. Mcdonald III

Chapter 29 - Limiting spinal cord injury by pharmacological intervention
Pages 463-484
John V. Priestley, Adina T. Michael-Titus, Wolfram Tetzlaff

Chapter 30 - Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications
Pages 485-502
Samuel David, Rubèn López-Vales, V. Wee Yong

Chapter 31 - Defeating inhibition of regeneration by scar and myelin components
Pages 503-522
James W. Fawcett, Martin E. Schwab, Laura Montani, Nicole Brazda, Hans Werner MÜller

Chapter 32 - Realizing the maximum potential of Schwann cells to promote recovery from spinal cord injury
Pages 523-540
Mary Bartlett Bunge, Patrick Mcghee Wood

Chapter 33 - Repair of central nervous system lesions by transplantation of olfactory ensheathing cells
Pages 541-549
Geoffrey Raisman, S.C. Barnett, Almudena RamΓ³n-Cueto

Chapter 34 - Cell transplantation: stem cells and precursor cells
Pages 551-561
Qilin Cao, Scott R. Whittemore

Chapter 35 - Gene therapy, neurotrophic factors and spinal cord regeneration
Pages 563-574
Armin Blesch, Itzhak Fischer, Mark H. Tuszynski

Chapter 36 - Scaffolds to promote spinal cord regeneration
Pages 575-594
S. Sakiyama-Elbert, P.J. Johnson, S.I. Hodgetts, G.W. Plant, A.R. Harvey

Chapter 37 - Molecular target discovery for neural repair in the functional genomics era
Pages 595-616
Joost Verhaagen, Ronald E. Van kesteren, Koen A.M. Bossers, Harold D. Macgillavry, Matthew R. Mason, August B. Smit

Chapter 38 - Combination therapies
Pages 617-636
M. Oudega, E.J. Bradbury, M.S. Ramer

Index
Pages 637-656


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