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Spinal and pontine α2-adrenoceptors have opposite effects on pain-related behavior in the neuropathic rat

✍ Scribed by Hong Wei; Antti Pertovaara


Book ID
113586436
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
363 KB
Volume
551
Category
Article
ISSN
0014-2999

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Effects of systemically administered cocaine on formalin-induced pain behavior and c-fos-like immunoreactivity in the spinal dorsal horn were studied in rats. During the whole observation period of 90 min, formalin-induced pain behavior was completely suppressed by cocaine (30 mg/kg i.p. followed by