Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives
โ Scribed by Masahisa Katsuno; Hiroaki Adachi; Fumiaki Tanaka; Gen Sobue
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 308 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0946-2716
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๐ SIMILAR VOLUMES
## Abstract Postural tremor is a common initial symptom in spinal and bulbar muscular atrophy (SBMA), but its pathophysiological mechanisms remain to be studied. This study was undertaken to examine the physiological mechanisms underlying postural tremor in SBMA. For eight patients (36โ63 years old
Spinal-bulbar muscular atrophy (SBMA) is a rare X-linked neuronopathy associated with an abnormal representation of androgen receptors in the nervous system. Standard nerve conduction and histopathological studies have disclosed the involvement of large myelinated sensory fibers in the spinal nerves