✍ Scribed by Joseph P. Hornak; Aric C. Smith; Jerzy Szumowski
No coin nor oath required. For personal study only.
The spin‐lattice relaxation time T~1~ of multicomponent tissues is often determined by fitting relaxation data to monoexponential functions. This process can lead to large errors in the relaxation time. We describe a procedure using chemical‐shift imaging (CSI) which separates the NMR signal into water and lipid components thus allowing the two signals to be individually analyzed for relaxation times. This procedure yields more representative relaxation times than those obtained by both monoexponential and biexponential fitting schemes.
📜 SIMILAR VOLUMES
1H NMR spin-lattice relaxation times (T1) of the N-CH3 proton resonances of phosphocreatine (PCr) and creatine (Cr) in water solutions were obtained using the 1,3,3,1 pulse sequence. These T1 values were equivalent to those obtained in D2O and water using either the conventional inversion-recovery e
## Abstract A new method for measuring spin‐lattice relaxation times and chemical exchange (CE) rate constants in multiple‐site exchanging systems is described. The method, chemical exchange and __T__~1~ measurement using progressive saturation (CUPS), was applied to determine __T__~1~s and analyze