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Spin equilibrium and quaternary structure change in hemoglobin A. Experiments on a quantitative probe of the stereochemical mechanism of hemoglobin cooperativity

✍ Scribed by Cho, Kar Cheong; Hopfield, J. J.


Book ID
126849721
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
945 KB
Volume
18
Category
Article
ISSN
0006-2960

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## Abstract Molecular dynamics (MD) simulations of human adult hemoglobin (HbA) were carried out for 45 ns in water with all degrees of freedom including bond stretching and without any artificial constraints. To perform such large‐scale simulations, one of the authors (M.S.) accelerated his own so