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Sphingosylphosphorylcholine activates dendritic cells, stimulating the production of interleukin-12

✍ Scribed by Ana Ceballos; Juan Sabatté; Karen Nahmod; Diego Martínez; Gabriela Salamone; Mónica Vermeulen; Julián Maggini; Horacio Salomón; Jorge Geffner


Book ID
108782075
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
642 KB
Volume
121
Category
Article
ISSN
0019-2805

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Prostaglandin (PG) D(2), and its metabolites, are known to be important mediators during acute and chronic inflammation. However, their functions during the early phases of the immune response are poorly documented. In the present study, we show that PGD(2 )inhibits, in a dose-dependent manner, the