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Sphingosine kinase 1 promotes tumor progression and confers malignancy phenotypes of colon cancer by regulating the focal adhesion kinase pathway and adhesion molecules

✍ Scribed by Huang, Jie-An


Book ID
120182369
Publisher
Spandidos Publications Ltd
Year
2012
Tongue
English
Weight
761 KB
Volume
42
Category
Article
ISSN
1019-6439

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## Abstract Focal adhesion kinase (FAK) is suggested to be intimately involved in the progression of malignancies. Our previous research has demonstrated that activation of cholecystokinin‐2 receptor (CCK2R) by gastrin stimulates a rapid activation of FAK pathway in human colon cancer cells. The pu