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Sphingosine kinase-1 mediates TNF- -induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flow

✍ Scribed by Chen, X.-L.


Book ID
118258384
Publisher
The American Physiological Society
Year
2004
Tongue
English
Weight
220 KB
Volume
287
Category
Article
ISSN
0363-6135

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## Abstract The level of adhesion molecules expressed at the endothelial cell surface is critical in the control of inflammation. Adenylate cyclase (AC) activity allowing cyclic adenosine monophosphate (cAMP) production can modulate the inflammatory process. We investigated the AC‐dependent modulat