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Sphingosine-kinase 1 and 2 contribute to oral sensitization and effector phase in a mouse model of food allergy

✍ Scribed by Susanne C. Diesner; Ana Olivera; Sandra Dillahunt; Cornelia Schultz; Thomas Watzlawek; Elisabeth Förster-Waldl; Arnold Pollak; Erika Jensen-Jarolim; Eva Untersmayr; Juan Rivera

Book ID: 116569738
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 777 KB
Volume: 141
Category: Article
ISSN: 0165-2478
DOI: 10.1016/j.imlet.2011.10.006

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN