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Sphingosine inhibits nitric oxide synthase from cerebellar granule cells differentiated in vitro

โœ Scribed by Paola Viani; Paola Giussani; Laura Riboni; Rosaria Bassi; Guido Tettamanti

Book ID
117111112
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
431 KB
Volume
454
Category
Article
ISSN
0014-5793

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## Abstract The role of endogenous neuronal nitric oxide synthase (nNOS) gene in the development of cerebellar granule neurons (CGNs) is conflicting. Here, we tested the effect of antisense oligos (ASโ€ODN) on the endogenous nNOS gene and the development of the CGNs in vitro. The expression of nNOS