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Sphingosine as an Inhibitor of Blood Clotting

โœ Scribed by HECHT, E.; SHAPIRO, D.


Book ID
121149589
Publisher
American Association for the Advancement of Science
Year
1957
Tongue
English
Weight
114 KB
Volume
125
Category
Article
ISSN
0036-8075

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The 24nyl ~hy~~~l-~~ 1. was syatbe&i and testesI for i~ibi~ of ~~~-~ Iyase. The carboo akeletoa was wepared by acylacion of a methioaiae imine with N-metboxy-N-methyl palmitatnide. The vinyl group was generated by thermal sulbxide eliiination. Reduction of both carbonyl groups and &protection gave P