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Sphingosine-1-phosphate stimulated connective tissue growth factor expression in human buccal fibroblasts: Inhibition by epigallocatechin-3-gallate

✍ Scribed by Sar, Jenny I-Chun; Yang, Chih-Jen; Tsai, Yi-Shin; Deng, Yi-Ting; Chen, Hsin-Ming; Chang, Hao-Hueng; Liu, Cheing-Meei

Book ID: 122556847
Publisher: Chinese Electronic Periodical Services
Year: 2015
Tongue: English
Weight: 468 KB
Volume: 114
Category: Article
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2013.08.004

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## Abstract Connective tissue growth factor (CTGF/CCN2) is a matricellular protein induced by transforming growth factor (TGF)‐β and intimately involved with tissue repair and overexpressed in various fibrotic conditions. We previously showed that keratinocytes in vitro downregulate TGF‐β‐induced e