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Sphingosine 1-phosphate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis

✍ Scribed by Qing-Fang Li; Chu-Tse Wu; Qiang Guo; Hua Wang; Li-Sheng Wang


Book ID
116296706
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
566 KB
Volume
371
Category
Article
ISSN
0006-291X

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In alcoholic liver disease, ethanol-induced damage to sinusoidal endothelial cells (SECs) appears to be important in the progression of liver damage. However, little is known about the mechanisms responsible for protection of SECs against ethanol-induced injury. To elucidate the role of sphingosine