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Sphingosine-1-phosphate and oligodendrocytes: From cell development to the treatment of multiple sclerosis

✍ Scribed by Rochelle P. Coelho; Harsimran S. Saini; Carmen Sato-Bigbee


Book ID
113865127
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
405 KB
Volume
91
Category
Article
ISSN
0090-6980

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✍ Cynthia K McClure; Pranab K Mishra πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 180 KB

The synthesis of a new pentacovalent oxaphospholene from a dienone, and its use as an enolate equivalent in the approach toward the syntheses of phosphonate analogs of sphingomyelin, sphingosine 1-phosphate and ceramide 1-phosphate are described. Condensation of the new P(V) reagent with an azodicar