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Sphingolipids in Neuroblastoma: Their Role in Drug Resistance Mechanisms

✍ Scribed by Hannie Sietsma; Anne Jan Dijkhuis; Willem Kamps; Jan Willem Kok


Book ID
110393654
Publisher
Springer
Year
2002
Tongue
English
Weight
57 KB
Volume
27
Category
Article
ISSN
0364-3190

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✍ Toshiyuki Yamaji; Keigo Kumagai; Nario Tomishige; Kentaro Hanada πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 124 KB

## Abstract Recent discoveries of two sphingolipid transfer proteins, CERT and FAPP2, have brought the field of sphingolipid metabolism to a more dynamic stage. CERT transfers ceramide from the endoplasmic reticulum (ER) to the Golgi apparatus, a step crucial for sphingomyelin (SM) synthesis. The p