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Spermine Binding to Parkinson’s Protein α-Synuclein and Its Disease-Related A30P and A53T Mutants

✍ Scribed by Grabenauer, Megan; Bernstein, Summer L.; Lee, Jennifer C.; Wyttenbach, Thomas; Dupuis, Nicholas F.; Gray, Harry B.; Winkler, Jay R.; Bowers, Michael T.


Book ID
126072916
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
973 KB
Volume
112
Category
Article
ISSN
0022-3654

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## Abstract Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione S‐transferase (GST) has detoxification and antioxidative functions. To screen genetic variations in GST for an effect on the onset age (OA) of PD, we typ