Tetraspan myelin protein PMP22 and demye
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Hans W. Müller
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Article
📅
2000
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John Wiley and Sons
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English
⚖ 60 KB
👁 2 views
It has been demonstrated that abnormal levels of PMP22 expression due to altered gene dosage in CMT1A neuropathy alters Schwann cell growth and differentiation. On the other hand, disease-related missense mutations within transmembrane domains of PMP22 disturb intracellular protein trafficking leadi