Sperm protein 17 is highly expressed in endometrial and cervical cancers
β Scribed by Fang-qiu Li; Qun Liu; Yan-ling Han; Bo Wu; Hong-lin Yin
- Book ID
- 115010148
- Publisher
- BioMed Central
- Year
- 2010
- Tongue
- English
- Weight
- 638 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1471-2407
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## Abstract Sperm protein 17 (Sp17) is an antigenic protein highly expressed in spermatozoa. Sp17 expression was demonstrated recently in multiple myeloma, suggesting that it may be a novel cancerβtestis antigen. Expression of Sp17 mRNA and protein was examined in human ovarian tumors. Sp17 mRNA wa
## Abstract We recently identified sperm protein 17 (Sp17) transcripts in esophageal squamous cell carcinomas (ESCCs) by differential display. This study was designed to determine the clinical significance of Sp17 protein in different stages of esophageal tumorigenesis and to test the hypothesis th