Sperm-induced ca2+oscillations in mouse maturing oocytes and postovulatory ageing eggs
โ Scribed by Manqi Deng; Jian Xin; Xiuying Huang; Fangzhen Sun
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 293 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1001-6538
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We previously demonstrated in the mouse oocyte that in vivo postovulatory aging significantly suppresses activity of the endoplasmic reticulum (ER) Ca 2ฯฉ -ATPase (Igarashi et al. 1997. Mol Reprod Dev 48:383-390). We undertook the present study to further examine the effects of oocyte aging on Ca 2ฯฉ
## Abstract The initiation of normal embryo development depends on the completion of all events of egg activation. In all species to date, egg activation requires an increase(s) in the intracellular concentration of calcium ([Ca^2+^]~i~), which is almost entirely mediated by inositol 1,4,5โtrisphos
## Abstract Maitotoxin (MTX), a potent marine toxin, activates Ca^2+^ entry via nonselective cation channels in a wide variety of cells. The identity of the channels involved in MTX action remains unknown. In mammalian sperm, Ca^2+^ entry through storeโoperated channels regulates a number of physio
## Abstract ## Background At fertilisation, mammalian oocytes are activated by oscillations of intracellular Ca^2+^ ([Ca^2+^]~i~). Phospholipase Cฮถ, which is introduced by fertilising spermatozoon, triggers [Ca^2+^]~i~ oscillations through the generation of inositol 1,4,5-triphosphate (IP~3~), whi