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Spektrophotometrische Bestimmung kation- und anionaktiver Bestandteile von Arzneimitteln nach Ionenpaarextraktion an Inertträgern Spectrophotometric

✍ Scribed by Jutta Riedl; Friedrich Moll


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
170 KB
Volume
318
Category
Article
ISSN
0365-6233

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✦ Synopsis


A solution of 2.0 g (0.01 mol) of 1 in 30 ml of DMF was treated with 3.0 ml(0.02 mol) of 2d and stirred at room temp. for 30 min. The precipitate was washed with DMF to give 1.8 g (60 %) of crude product 4, mp. 193-198", vco 1720cm-', mol. mass294 (ms). 1.8 g (6 mmol) 4 was dissolved in 16 ml of glacial acetic acid and refluxed for 4 h. After cooling, the solid product was recrystallized from acetic acid to yield 1.4 g (R5 %) of yellow needle crystals, mp. 292-294'. UV (MeOH): hmax (log E)