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Speeding Up Three-Dimensional Protein NMR Experiments to a Few Minutes

✍ Scribed by Schanda, Paul; Van Melckebeke, Hélène; Brutscher, Bernhard


Book ID
120194946
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
131 KB
Volume
128
Category
Article
ISSN
0002-7863

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Nuclear magnetic resonance is an important tool for high-resolution structural studies of proteins. It demands high protein concentration and high purity; however, the expression of proteins at high levels often leads to protein aggregation and the protein purification step can correspond to a high