✦ LIBER ✦
Speed congenics: a classic technique in the fast lane (relatively speaking)
✍ Scribed by Edward Wakeland; Laurence Morel; Karen Achey; Mary Yui; Jeff Longmate
- Book ID
- 104298708
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 845 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
✦ Synopsis
Marker-assisted selection protocol (MASP)-based strategies produce congenic strains with the target gene contained on clearly defined donor-derived genomic intervals in less than half the member of generations required by the classic protocol. Thus, the quality and speed of congenic strain construction are enhanced by this methodology. Here, Edward Wakeland and colleagues compare various MASP-based strategies and discuss their advantages with reference to immunological traits.