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Speech Dysfluency Exacerbated by Levodopa in Parkinson's Disease

✍ Scribed by Elan D. Louis; Linda Winfield; Stanley Fahn; Blair Ford

Book ID
102945029
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
840 KB
Volume
16
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

The role of dopamine in the modulation of speech fluency is complex. In this report we describe two patients with Parkinson's disease whose speech dysfluency was exacerbated by the administration of levodopa. In doing so, we extend the observation that dopaminergic mechanisms may be involved in the regulation of speech fluency. It is important for clinicians to recognize that, in some instances, dopaminergic replacement therapy may exacerbate an underlying dysfluency syndrome in PD.

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