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Spectrum of β-Thalassemia Mutations in Egypt

✍ Scribed by Waye, J. S.; Borys, S.; Eng, B.; Patterson, M.; Chui, D. H. K.; El-Din, O.M.K. Badr; Aref, M. Khairy; Afify, Z.


Book ID
118146695
Publisher
Informa plc
Year
1999
Tongue
English
Weight
366 KB
Volume
23
Category
Article
ISSN
0363-0269

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The relative frequency of different beta-thalassemia mutations and their association with beta-globin haplotypes were studied in patients from the Nile delta region, Egypt, by means of the polymerase chain reaction, oligonucleotide hybridization and restriction analysis. We found that 8 mutations ac