The suggested incidence of cystic fibrosis (CF) in Asian migrants (Indians and Pakistanis) in the United Kingdom is about 1 in 10,000 to 12,000 [Goodchild et al., 1974]. There are no large studies on CF in Asian Indians. The disorder is thought to be rare and most studies from the Asian subcontinent
Spectrum of mutations in cystic fibrosis
β Scribed by Garry R. Cutting
- Publisher
- Springer US
- Year
- 1993
- Tongue
- English
- Weight
- 418 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0145-479X
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The cystic fibrosis transmembrane conductance regulator (CFTR) gene of 110 cystic fibrosis (CF) patients from the south-west of Germany was screened for 12 different mutations. This analysis resulted in an identification of 79% of all CF mutations and a complete genotype in 66% of the families. The
We have collated the results of cystic fibrosis (CF) mutation analysis conducted in 19 laboratories in France. We have analyzed 7,420 CF alleles, demonstrating a total of 310 different mutations including 24 not reported previously, accounting for 93.56% of CF genes. The most common were F508del (67