Spectrum of CFTR mutations in the middle
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J.J. Tellería; M.J. Alonso; C. Calvo; M. Alonso; A. Blanco
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Article
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1999
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John Wiley and Sons
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English
⚖ 18 KB
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We have analyzed 39 unrelated cystic fibrosis (CF) families by denaturing gradient gel electrophoresis (DGGE) and direct sequencing in order to determine the spectrum of CF mutations in our population. This approach has allowed us to detect 72 out of the 78 CF chromosomes (92.3%). The DF508 mutation