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Spectroscopic study of conformational changes in subdomain 1 of G-actin: influence of divalent cations

✍ Scribed by Nyitrai, M.; Hild, G.; Belágyi, J.; Somogyi, B.


Book ID
119411115
Publisher
Biophysical Society
Year
1997
Tongue
English
Weight
981 KB
Volume
73
Category
Article
ISSN
0006-3495

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Gelsolin, a calcium and inositol phospholipid-sensitive protein, regulates actin filament length. Its activity is complex (capping, severing, etc.) and is supported by several functional domains. The N-terminal domain alone (S1), in particular, is able to impede actin polymerization. Our investigati