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Spectroscopic and Molecular Modeling Studies of the Interaction Between 4′-O-(α-L-Oleandrosyl)daunorubicin and Human Serum Albumin and Its Analytical Application

✍ Scribed by Ruina Huo; Cui Li; Fengling Cui; Guisheng Zhang; Qingfeng Liu; Xiaojun Yao


Publisher
Springer
Year
2011
Tongue
English
Weight
332 KB
Volume
22
Category
Article
ISSN
1053-0509

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## Abstract In this study, the interaction between cytidine and human serum albumin (HSA) was investigated for the first time by fluorescence spectroscopy in combination with UV absorption spectrum and molecular modeling under simulative physiological conditions. Experimental results indicated that