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Spectroscopic and molecular modeling of the binding of meso-tetrakis(4-hydroxyphenyl)porphyrin to human serum albumin

✍ Scribed by Wenting An; Yong Jiao; Chuan Dong; Cheng Yang; Yoshihisa Inoue; Shaomin Shuang


Book ID
108115000
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
716 KB
Volume
81
Category
Article
ISSN
0143-7208

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The interaction between cationic porphyrin, a potential valuable antitumor and antibiotic drug, and human serum albumin (HSA) was investigated using spectroscopy methods. The binding constants were obtained using fluorescence quenching method (K SV ΒΌ (3.24 AE 0.29) Γ‚ 10 4 M Γ€1 ) and surface plasmon