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Spectroscopic and Binding Properties of Berberine to DNA and Its Application to DNA Detection

✍ Scribed by Li, Wen-You; Lu, Hua; Xu, Chun-Xiang; Zhang, Jie-Bing; Lu, Zu-Hong

Book ID
120276623
Publisher
Taylor and Francis Group
Year
1998
Tongue
English
Weight
342 KB
Volume
31
Category
Article
ISSN
0038-7010

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The interaction of two natural protoberberine plant alkaloids berberine and palmatine with tRNA phe was studied using various biophysical techniques and molecular modeling and the data were compared with the binding of the classical DNA intercalator, ethidium. Circular dichroic studies revealed that