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Spectroscopic analysis of imidazolidines. Part II: 1H NMR spectroscopy and conformational analysis of 1,2 and 1,3-diarylimidazolidines

✍ Scribed by Alejandra Salemo; Graciela Buldain; Isabel A. Perillo

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
37 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

^1^H NMR spectra of a series of 1,2 and 1,3‐diarylimidazolidines are analyzed and correlated with their conformational features. Results were interpreted on the basis of chemical shifts and coupling constants of hydrogen atoms and confirmed by ID nOe difference experiments. 1,3‐Diarylimidazolidines (1–7) show a fast inversion of the N‐aryl nitrogen in all studied cases. 1,2‐Diaryl‐3‐methyl (or benzyl) imidazolidines (8–13) display a preferential conformation with a transoid orientation of N~3~ and C~2~ substituents.

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